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Biomolecular NMR

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Penn State College of Medicine’s NMR Facility was created in 2006 through financial support from the NIH shared instrumentation grant (S10 RR021172), the US Department of the Navy and the Pennsylvania Department of Health through the Tobacco Settlement Funds and the Penn State College of Medicine.

Its mission remains to facilitate investigators to use multiple modern NMR applications, including structure elucidation of small molecules, triple resonance experiments of biomolecules, fragment-based drug discovery, metabolomic and tissue analyses.

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Instrumentation and Services

The NMR instrumentation include a 500 MHz Ultra-shielded Magnet with Bruker Avance II console and a 600 MHz Ultra-Shield Magnet with Bruker Avance Neo console. The 600 MHz spectrometer is equipped with a cryoprobe and a SampleCase for automation.

PROBES

All probes are equipped with a z-gradient coil.

Procedures, Protocols and Forms

Citation Expand answer

All publications, press releases or other documents that result from the utilization of any Penn State College of Medicine Institutional Research Resources including funding, tools, services or support are required to include the following citation:

“The NMR facility services and instruments used in this project were funded, in part, by the Pennsylvania State University College of Medicine via the Office of the Vice Dean of Research and Graduate Students and the Pennsylvania Department of Health using Tobacco Settlement Funds (CURE). The content is solely the responsibility of the authors and does not necessarily represent the official views of the University or College of Medicine. The Pennsylvania Department of Health specifically disclaims responsibility for any analyses, interpretations or conclusions.”

Working with the Core

Location Expand answer

The NMR facility is located in Room C2818, Biomedical Research building in the College of Medicine.

Fees Expand answer

All consultation is provided free of charge. For additional information, please contact the Facility Manager, Dr. Jyh-Ming Lin, at jml47@psu.edu or the Scientific Director, Dr Tian Fang, at ftian@pennstatehealth.psu.edu.

Contact the Core Expand answer