Penn State Health Milton S. Hershey Medical Center’s dermatology department is dedicated to expanding knowledge about many dermatological conditions by doing research in the laboratory, as well as in the clinic.
The department’s mission is to be a nationally recognized leader in research by:
- Growing clinical research
- Recruiting physician researchers to advance knowledge of skin disease and treatment
- Increasing dermatology research endowment funds in order to support the research mission
- Expanding collaborative research with investigators at Penn State University Park
- Developing research initiatives on quality of health care delivery in dermatology
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Diane M. Thiboutot, MD, is an endowed professor and vice chair for research in the Department of Dermatology at Penn State College of Medicine.
She is also associate dean for clinical and translational research educator for Penn State College of Medicine and associate director of Penn State Clinical and Translational Science Institute.
The dermatology clinical trials office works to enhance, foster, and promote organized clinical research within Penn State Health Milton S. Hershey Medical Center. The office assists from initiation through completion of the study, efficiently executing tasks that include confidentiality agreements, recruitment, regulatory, budgetary and data collection/procedures.
Meet the Team
- Amy Longenecker, BSN, RN, CCRC, Clinical Research Specialist – Manager
- Melissa Butt, MPH, Research Project Manager
- Samantha Gettle, LPN, CCRC, Clinical Research Associate II
- Kassidy Shumaker, Research Technologist I
- Tierney Wallace, BA, Clinical Research Associate I
View active dermatology clinical trials in StudyFinder, our searchable database of clinical research taking place at Penn State Health Milton S. Hershey Medical Center and Penn State College of Medicine.
Topics being studied include:
- Acne: Researchers are evaluating an investigational topical solution (Botox) versus placebo when applied to the forehead to treat acne.
- Lupus: Researchers are studying the effectiveness of an experimental medication for discoid lupus erythematosus and subacute cutaneous lupus erythematosus, two conditions that involve lesions.
- Psoriasis: Researchers are studying effective treatment for chronic plaque psoriasis.
- Hidradenitis suppurativa: Researchers are studying effective treatments for hidradenitis suppurativa.
Learn More About Clinical Research
- Read our clinical research FAQs
- Become a healthy volunteer
- See latest Penn State Health and Penn State College of Medicine clinical research news
Contact the Department
The basic and translational science research teams at Penn State Dermatology are using leading-edge technologies to understand both normal skin biology and a number of inflammatory and autoimmune skin diseases. Within the dermatology laboratories, researcheres use a variety of model systems, including human patient samples, to discover the mechanisms underlying disease development and identify novel biological targets for future therapies. Researcheres work closely with clinical colleagues, bioinformaticians and other researchers to provide a multidisciplinary team approach to combatting skin diseases.
- Amanda M. Nelson, PhD – Assistant Professor of Dermatology, principal investigator
- Diane M. Thiboutot, MD – Professor of Dermatology, principal investigator, Vice Chair for Research in the Department of Dermatology, Director of Research Education for Penn State Clinical and Translational Science Institute
- Stephanie Schell – Postdoctoral scholar
- Andrea Schneider – MD/PhD student
- Zachary Nolan – MD/PhD student
- Mackenzie Sennett – MD/PhD student
- Zhaoyuan Cong – Technician
- Kathy Gilliland – Research administrator
- Ryan Hobbs, PhD – Assistant Professor of Dermatology, prinicpal investigator
- Ting Gao – Technician
- Robert Feehan, PhD – Postdoctoral scholar
- Elizabeth Lesko – PhD student
- Natella Maglakelidze – MD/PhD student
- Acne: The full pathogenesis of acne is incomplete. The Nelson/Thiboutot Lab is interested in understanding the mechanisms of a variety of agents, including isotretinoin, on sebocyte biology and sebum production.
- Skin microbiome: Each individual has a unique skin microbiome. With the NIH Human Microbiome Project, many research studies are focused on identifying and understanding the role of skin microbes and microbe communities in health and disease states. The Nelson/Thiboutot lab is focused on the understanding the skin microbiome in acne and hidradenitis suppurativa as well as how the skin microbiome responds to or is altered during the course of treatment for each disease.
- Hidradenitis suppurativa (HS): HS is a chronic, painful inflammatory skin disease. The underlying cause of HS is not fully known. The Nelson Lab has numerous projects focused on elucidating the etiology of HS, with the hope of that basic science research on HS pathogenesis will accelerate drug discovery for this devastating, prevalent and difficult-to-treat disease.
- Non-melanoma skin cancer: Both the Hobbs Lab and the Nelson Lab have a shared interest in non-melanoma skin cancer. Dr. Nelson’s team is focused on understanding the role of the innate immune system in squamous and basal cell carcinoma initiation and progression. Dr. Hobbs’s team studies the cellular mechanisms behind the development and progression of skin cancers.
- Industry partnerships: The Nelson/Thiboutot lab works in conjunction with our industry partners to perform drug screening on skin cell lines to identify novel mechanism, targets and therapeutics for the treatment of acne. We are also involved in in the design of investigator-initiated trials.
The Department of Dermatology participates in the Stem Cell and Regenerative Biology Program at Penn State Health Milton S. Hershey Medical Center and Penn State College of Medicine.
This program aims to bring together scientists and medical professionals with research interests in various areas of stem cell biology, such as regenerative medicine, disease modeling and cancer research.
More About Dermatology
Upcoming continuing education events in dermatology, if available, are listed below.
The Department of Dermatology offers Grand Rounds once a month during the academic year (September through June).
Patient volunteers are available for examination from 8:30 to 9:30 a.m. in the dermatology clinic, Suite 100 of University Physician Center in Hershey, Pa. The case discussions are held 9:30 to 11 a.m. The conferences are attended by a large number of dermatologists from the central Pennsylvania area, many of whom invite patients with challenging diagnostic or therapeutic problems.
The program also invites several visiting professors each year. The visiting professors participate in the case conference and also present a lecture from 11 a.m. to noon.
Penn State College of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Penn State College of Medicine designates this live activity for a maximum of 3 AMA PRA Category 1 credit(s)TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
All health care professionals with an interest in dermatology are welcome to attend the meetings.
Through Penn State College of Medicine, the Department of Dermatology offers educational programs for medical students, residents and fellows, all with a research component.
The Department of Dermatology specializes and cares for patients with all types of skin, hair and nail disorders.
The department’s team of physicians specializes in pediatric, adult, surgical and pathological aspects of skin disease. The team provides numerous sub-specialty services, including patch testing, occupational dermatology, dermatopathology, cosmetic dermatology and Mohs surgery, as well as many others.