A number of people support the work of the Center for Orthopaedic Research and Translational Science in the Department of Orthopaedics and Rehabilitation at Penn State College of Medicine.
The multidisciplinary foci of CORTS include:
- Molecular biology of cartilage development and osteoarthritis
- Transgenic animal models of musculoskeletal disease
- Bone and cartilage cell biology
- Biophysical signal transduction as it applies to orthopaedic problems
- Pathophysiology of age-related and post-menopausal osteoporosis
- Computational biomechanics
- Effects of exercise on bone and cartilage
- Assessment of orthopaedic implant function and failure
- Matrix metalloproteinase expression in connective tissue
- Tendon/ligament mechanics and mechanobiology
- Roles of non-coding RNAs and retrotransposons in skeletal biology
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