The Center for Orthopaedic Research and Translational Science in the Department of Orthopaedics and Rehabilitation has more than 5,000 square feet of laboratory space. Our resources include state-of-the-art equipment for experimental and computational biomechanics, molecular biology, cell culture, image analysis and cellular electrophysiology.
Major equipment includes three cell-culture facilities, a dedicated darkroom with digital microscopic imaging and gel documentation facilities, HPLC, equipment for histomorphometric analysis of hard and soft tissue, Interlaken servohydraulic and Instron materials testing machines (with a fully supported computer network for data analysis), and graphic presentation.
We also have a surgical suite suitable for small animal surgery, cadaveric specimen preparation and demonstration of surgical techniques.
Areas are dedicated to the following:
- Cell and molecular biology
- Tissue culture
- Image analysis
- Fluorescent microscopy
- Computer modeling
Additionally, all departmental members have access to four mass spectrometers, flow cytometry and flow sorting, automated sequencing, histological services, real-time PCR, confocal microscopy, laser dissection microscopy, transmission electron microscopy, DNA array analysis and custom DNA and protein array synthesis.