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Center for Orthopaedic Research and Translational Science Facilities

The Center for Orthopaedic Research and Translational Science in the Department of Orthopaedics and Rehabilitation has more than 5,000 square feet of laboratory space. Our resources include state-of-the-art equipment for experimental and computational biomechanics, molecular biology, cell culture, image analysis and cellular electrophysiology.

Major equipment includes three cell-culture facilities, a dedicated darkroom with digital microscopic imaging and gel documentation facilities, HPLC, equipment for histomorphometric analysis of hard and soft tissue, Interlaken servohydraulic and Instron materials testing machines (with a fully supported computer network for data analysis), and graphic presentation.

We also have a surgical suite suitable for small animal surgery, cadaveric specimen preparation and demonstration of surgical techniques.

Areas are dedicated to the following:

  • Biomechanics
  • Cell and molecular biology
  • Biochemistry
  • Microbiology
  • Tissue culture
  • Histomorphometry
  • Image analysis
  • Fluorescent microscopy
  • Electrophysiology
  • Computer modeling

Additionally, all departmental members have access to four mass spectrometers, flow cytometry and flow sorting, automated sequencing, histological services, real-time PCR, confocal microscopy, laser dissection microscopy, transmission electron microscopy, DNA array analysis and custom DNA and protein array synthesis.